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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNMA1 All Species: 16.67
Human Site: S1203 Identified Species: 36.67
UniProt: Q12791 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12791 NP_001154824.1 1236 137560 S1203 S Q S S S K K S S S V H S I P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta O18867 1151 128915 S1118 S Q S S S K K S S S V H S I P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q08460 1209 134378 S1176 S Q S S S K K S S S V H S I P
Rat Rattus norvegicus Q62976 1209 134356 S1177 S Q S S S K K S S S V H S I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510131 822 92544 S790 H S S S K K S S S V H S I P S
Chicken Gallus gallus Q8AYS8 1137 127628 S1105 Y S S S K K S S S V H S I P S
Frog Xenopus laevis Q90ZC7 1196 134483 I1163 E N N Y P R N I Q I K P M S T
Zebra Danio Brachydanio rerio NP_001139072 1184 133307 P1148 D E A E N A Y P R N I Q I K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03720 1200 133083 F1157 L L P T D Q V F V L M Q F D P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95V25 1140 129511 N1108 M K R Y V I T N P P A E L R I
Sea Urchin Strong. purpuratus XP_783726 1307 143907 A1250 T Q A P T S P A L S S V P L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93 N.A. N.A. 94 93.9 N.A. 62.1 87.8 84 84.3 N.A. 54.8 N.A. 51.2 49
Protein Similarity: 100 N.A. 93.1 N.A. N.A. 94.3 94.1 N.A. 63.7 89.5 88.1 88.3 N.A. 68.5 N.A. 64.8 63.5
P-Site Identity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 33.3 33.3 0 6.6 N.A. 6.6 N.A. 0 20
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 33.3 33.3 13.3 40 N.A. 26.6 N.A. 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 10 0 10 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 19 37 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 10 0 10 10 0 28 37 10 % I
% Lys: 0 10 0 0 19 55 37 0 0 0 10 0 0 10 0 % K
% Leu: 10 10 0 0 0 0 0 0 10 10 0 0 10 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % M
% Asn: 0 10 10 0 10 0 10 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 10 10 0 10 10 10 10 0 10 10 19 64 % P
% Gln: 0 46 0 0 0 10 0 0 10 0 0 19 0 0 0 % Q
% Arg: 0 0 10 0 0 10 0 0 10 0 0 0 0 10 0 % R
% Ser: 37 19 55 55 37 10 19 55 55 46 10 19 37 10 19 % S
% Thr: 10 0 0 10 10 0 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 0 10 0 10 19 37 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 19 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _